Abstract: How to evaluate the groundwater resources of the incomplete groundwater system on the west bank of the Yellow River in the Northern Shaanxi Energy and Chemical Industry Base is a difficult problem. In this study a regional model (1 km×1 km) was constructed, which provided specified head boundaries for the imbedded model (100 m×100 m). By using the results of simulation of six different exploitation plans, the influence of water mining on the adjacent well fields and the regional groundwater system was analyzed, and the interrelation between various sub-spring domains of the Tianqiao karst system and influence of the construction of the Wanjiazhai Reservoir on groundwater circulation was identified. At last the exploitable water resources in the water source area on the west bank of the Yellow River is estimated at 60×104 m3/d.