Abstract: The fault structure and the Lower Cambrian Niutitang Formation are widely distributed in northern Guizhou of the upper Yangtze platform.The Niutitang Formation is a set of marine sedimentary and is mainly com-posed of shelf deposit,especially deep water shelf deposit which is favorable for the formation of shale gas.Informa-tion from well Suiye 1 in the Niutitang Formation revealed that the upper deposit was a good cap rock,and the ad-vantageous potential shale mainly located in the lower,with high organic matter abundance,high maturity,a large number of micro-fissure,high gas-bearing properties and favorable preservation condition.According to the compre-hensive analysis of the shale gas geological characteristics,we proposed that the Niutitang Formation was a good prospect for shale gas exploration.